| Brain |
n/a |
Alliance A221208: Randomized Phase II Study: Corticosteroids + Bevacizumab vs. Corticosteroids +
Placebo (BEST) for Radionecrosis After Radiosurgery for Brain Metastases |
Trial Details
|
| Brain |
Glioblastoma |
A221101: A Phase III Randomized, Double-Blind Placebo Controlled Study of Armodafinil (Nuvigil®)
To Reduce Cancer-Related Fatigue in Patients With High Grade Glioma |
Trial Details
|
| Brain (Cancer Control) |
n/a |
NRG CC003: Randomized Phase II/III Trial of Prophylactic Cranial Irradiation With or Without
Hippocampal Avoidance for Small Cell Lung Cancer |
Trial Details
|
| Brain (Cancer Control) |
n/a |
NRG-CC001: A Randomized Phase III Trial of Memantine and Whole-Brain Radiotherapy With or
Without Hippocampal Avoidance in Patients With Brain Metastases
|
Trial Details
|
| Breast |
n/a |
Alliance A011401: Randomized Phase III Trial Evaluating the Role of Weight Loss in Adjuvant
Treatment of Overweight and Obese Women With Early Breast Cancer
|
Trial Details
|
| Breast |
n/a |
SPI-GCF-301: Randomized Trial of SPI-2012 Versus Pegfilgrastim in the Management of Chemotherapy
Induced Neutropenia in Breast Cancer Patients Receiving Docetaxel and Cyclophosphamide (TC)
(ADVANCE) |
Trial Details
|
| Breast |
n/a |
TARGIT-B: An International Randomised Controlled Trial to Compare Targeted Intra-operative
Radiotherapy Boost With Conventional External Beam Radiotherapy Boost After Lumpectomy for Breast
Cancer in Women With a High Risk of Local Recurrence.
|
Trial Details
|
| Breast |
n/a |
TARGIT-R: TARGIT R: Targeted Intraoperative Radiotherapy (TARGIT) Registry Database |
Trial Details
|
| Breast |
n/a |
TARGIT-US: Targeted Intraoperative Radiotherapy United States (TARGIT-US) Phase IV Registry
Trial: A Registry Trial of Targeted Intraoperative Radiation Therapy Following Breast-conserving
|
Trial Details
|
| Breast |
Adjuvant |
NRG-BR003: A Randomized Phase III Trial of Adjuvant Therapy Comparing Doxorubicin Plus
Cyclophosphamide Followed by Weekly Paclitaxel With or Without Carboplatin for Node-Positive or
High-Risk Node-Negative Triple-Negative Invasive Breast Cancer |
Trial Details
|
| Breast |
Adjuvant/Neoadjuvant |
CTSU/ECOG E1Z11: A Cohort Study to Evaluate Genetic Predictors of Aromatase Inhibitor
Musculoskeletal Symptoms (AIMSS)
|
Trial Details
|
| Breast |
Adjuvant/Neoadjuvant |
NSABP B-51: A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chest Wall and
Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients With Positive Axillary Nodes
Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After
Neoadjuvant Chemotherapy |
Trial Details
|
| Breast |
Metastatic |
NRG-BR001: A Phase 1 Study of Stereotactic Body Radiotherapy (SBRT) for the Treatment of
Multiple Metastases
|
Trial Details
|
| Breast |
Neoadjuvant |
Alliance A011202: A Randomized Phase III Trial Comparing Axillary Lymph Node Dissection to
Axillary Radiation in Breast Cancer Patients (cT1-3 N1) Who Have Positive Sentinel Lymph Node
Disease After Neoadjuvant Chemotherapy
|
Trial Details
|
| Breast |
Neoadjuvant |
Prospective Neo-adjuvant REGISTRY Trial Linking MammaPrint, Subtyping and Treatment Response:
Neoadjuvant Breast Registry - Symphony Trial (NBRST) (Pronounced "in Breast") |
Trial Details
|
| Breast (Cancer Control) |
n/a |
A221102: Randomized Double-Blind Placebo Controlled Study of Testosterone in the Adjuvant
Treatment of Postmenopausal Women With Aromatase Inhibitor Induced Arthralgias |
Trial Details
|
| Breast (Treatment) |
n/a |
NSABP B-57-I: Palbociclib Collaborative Adjuvant Study: A Randomized Phase III Trial of
Palbociclib With Standard Adjuvant Endocrine Therapy Versus Standard Adjuvant Endocrine Therapy
Alone for Hormone Receptor Positive (HR+) / Human Epidermal Growth Factor Receptor 2 (HER2)-Negative
Early Breast Cancer |
Trial Details
|
| Childrens |
n/a |
ACCRN07: Protocol for the Enrollment on the Official COG Registry, The Childhood Cancer Research
Network (CCRN) Children s Oncology Group
|
Trial Details
|
| Childrens |
n/a |
AHOD1331: A Randomized Phase III Study of Brentuximab Vedotin (SGN-35) for Newly Diagnosed
High-Risk Classical Hodgkin Lymphoma (cHL) in Children and Adolescents |
Trial Details
|
| Childrens |
n/a |
AOST1421: A Phase 2 Study of Human-Mouse Chimeric Anti-Disialoganglioside Monoclonal Antibody
ch14.18 (Dinutuximab, NSC# 764038) in Combination With Sargramostim (GM-CSF) in Patients With
Recurrent Osteosarcoma |
Trial Details
|
| Childrens |
n/a |
APEC14B1: The Project: Every Child Protocol: A Registry, Eligibility Screening, Biology and
Outcome Study |
Trial Details
|
| Childrens |
ALL |
AALL08B1: Risk-Based Classification System of Patients with Newly Diagnosed Acute Lymphoblastic
Leukemia |
Trial Details
|
| Childrens |
ALL |
AALL0932: Treatment of Patients with Newly Diagnosed Standard Risk B-Precursor Acute
Lymphoblastic Leukemia (ALL)
|
Trial Details
|
| Childrens |
ALL |
AALL1131, A Phase III Randomized Trial for Newly Diagnosed High Risk B-precursor Acute
Lymphoblastic Leukemia (ALL) Testing Clofarabine (IND# 73789) in the Very High Risk Stratum. |
Trial Details
|
| Childrens |
ALL |
AALL1231: A Phase III Randomized Trial Investigating Bortezomib (NSC# 681239) on a Modified
Augmented BFM (ABFM) Backbone in Newly Diagnosed T-Lymphoblastic Leukemia (T-ALL) and
T-Lymphoblastic Lymphoma (T-LLy) |
Trial Details
|
| Childrens |
ALL |
AALL1331:Risk-Stratified Randomized Phase III Testing of Blinatumomab (NSC#765986) in First
Relapse of Childhood B-Lymphoblastic Leukemia (B-ALL)
|
Trial Details
|
| Childrens |
ALL |
ABTR01B1: Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples
from Young Patients with Cancer |
Trial Details
|
| Childrens |
AML |
AAML08B1: Biology Study of Transient Myeloproliferative Disorder (TMD) in Children with Down
Syndrome (DS) |
Trial Details
|
| Childrens |
AML |
AAML1031, A Phase III Randomized Trial for Patients with de novo AML using Bortezomib (IND#
58443) and Sorafenib (IND# 69896) for Patients with High Allelic Ratio FLT3/ITD |
Trial Details
|
| Childrens |
AML |
AAML1331: A Phase III Study for Patients With Newly Diagnosed Acute Promyelocytic Leukemia (APL)
Using Arsenic Trioxide and All-trans Retinoic Acid |
Trial Details
|
| Childrens |
AML |
ANHL04B1: Collecting and Storing Tissue Samples from Patients with Rare or Cutaneous Non-Hodgkin
Lymphoma |
Trial Details
|
| Childrens |
CNS |
ACNS0332: Chemotherapy and Radiation Therapy in Treating Young Patients with Newly Diagnosed,
Previously Untreated, High-Risk Medulloblastoma or Supratentorial Primitive Neuroectodermal Turn |
Trial Details
|
| Childrens |
CNS |
ACNS0831, Phase III Randomized Trial of Post-Radiation Chemotherapy in Patients with Newly
Diagnosed Ependymoma Ages 1 to 21 Years. |
Trial Details
|
| Childrens |
CNS |
ACNS1123: Phase 2 Trial of Response-Based Radiation Therapy for Patients With Localized Central
Nervous System Germ Cell Tumors (CNS GCT) |
Trial Details
|
| Childrens |
CNS |
ALTE07C1: Neuropsychological and Behavioral Testing in Young Patients with Medulloblastoma or
Supratentorial Primitive Neuroectodermal Tumor (PNET) |
Trial Details
|
| Childrens |
Ewing Sarcoma |
AEWS07B1: Collecting and Storing Biological Samples From Patients with Ewing Sarcoma |
Trial Details
|
| Childrens |
Ewing Sarcoma |
AEWS1221: Randomized Phase 3 Trial Evaluating the Addition of the IGF-1R Monoclonal Antibody
Ganitumab (AMG 479, NSC# 750008) to Multiagent Chemotherapy for Patients With Newly Diagnosed
Metastatic Ewing Sarcoma |
Trial Details
|
| Childrens |
Liver Neuroblastoma |
AHEP0731: Combination Chemotherapy in Treating Young Patients with Newly Diagnosed Liver Cancer |
Trial Details
|
| Childrens |
Neuroblastoma |
ANBL00B1: Biomarkers in Tumor Tissue Samples from Patients with Newly Diagnosed Neuroblastoma or
Ganglioneuroblastoma |
Trial Details
|
| Childrens |
Neuroblastoma |
ANBL1221: A Phase II Randomized Trial of Irinotecan/Temozolomide With Temsirolimus (NSC# 683864,
IND# 61010) or Chimeric 14.18 Antibody (ch14.18) (NSC# 623408, IND# 4308) in Children With
Refractory, Relapsed or Progressive Neuroblastoma
|
Trial Details
|
| Childrens |
Neuroblastoma |
ANBL1232: Utilizing Response- and Biology-Based Risk Factors to Guide Therapy in Patients With
Non-high-risk Neuroblastoma
|
Trial Details
|
| Childrens |
Renal |
AREN03B2: Renal Tumors Classification, Biology, and Banking Study |
Trial Details
|
| Childrens |
Soft Tissue Sarcoma |
COG D9902: Collecting and Storing Tissue, Blood, and Bone Marrow Samples from Patients with
Rhabdomyosarcoma or Other Soft Tissue Sarcoma
|
Trial Details
|
| Colorectal |
n/a |
ARGO (NSABP C-13): A Phase III Randomized Placebo-Controlled Study Evaluating Regorafenib
Following Completion of Standard Chemotherapy for Patients With Stage III Colon Cancer |
Trial Details
|
| Colorectal |
n/a |
NSABP MPR-1: NSABP Patient Registry and Biospecimen Profiling Repository |
Trial Details
|
| Colorectal |
Colon |
Alliance/NCCTG N1048: A Phase II/III Trial of Neoadjuvant FOLFOX, With Selective Use of Combined
Modality Chemoradiation Versus Preoperative Combined Modality Chemoradiation for Locally Advanced
Rectal Cancer Patients Undergoing Low Anterior Resection With Total Mesorectal Excision |
Trial Details
|
| General Adult |
Oncology |
National Oncologic PET Registry (NOPR) |
Trial Details
|
| Genitourinary (Treatment) |
n/a |
RTOG 0924: Androgen Deprivation Therapy and High Dose Radiotherapy With or Without Whole-Pelvic
Radiotherapy in Unfavorable Intermediate or Favorable High Risk Prostate Cancer: A Phase III
Randomized Trial
|
Trial Details
|
| Genitourinary (Treatment) |
n/a |
RTOG 0926: A Phase II Protocol for Patients With Stage T1 Bladder Cancer to Evaluate Selective
Bladder Preserving Treatment by Radiation Therapy Concurrent With Radiosensitizing Chemotherapy
Following a Thorough Transurethral Surgical Re-Staging |
Trial Details
|
| GYN Malignancies (Cancer Control) |
n/a |
GOG-3005:A Phase 3 Placebo-Controlled Study of Carboplatin/Paclitaxel With or Without Concurrent
and Continuation Maintenance Veliparib (PARP Inhibitor) in Subjects With Previously Untreated Stages
III or IV High-Grade Serous Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer |
Trial Details
|
| Gynecologic |
Cervical |
GOG 0263: Randomized Phase III Clinical Trial of Adjuvant Radiation Versus Chemoradiation in
Intermediate Risk, Stage I/IIA Cervical Cancer Treated With Initial Radical Hysterectomy and Pelvic
Lymphadenectomy. |
Trial Details
|
| Gynecologic |
Endometrial |
GOG 0238: A Randomized Trial of Pelvic Irradiation with or without Concurrent Weekly Cisplatin
in Patients with Pelvic-only Recurrence of Carcinoma of the Uterine Corpus. |
Trial Details
|
| Gynecologic |
Ovarian |
MORab-003-011: A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study to Assess the
Efficacy and Safety of Farletuzumab (MORAb 003) in Combination With Carboplatin Plus Paclitaxel or
Carboplatin Plus Pegylated Liposomal Doxorubicin (PLD) in Subjects With Low CA125 Platinum-Sensitive
Ovarian Cancer |
Trial Details
|
| Gynecologic |
Ovarian |
PR-30-5017: A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of
Niraparib Maintenance Treatment in Patients With Advanced Ovarian Cancer Following Response on
Front-Line Platinum-Based Chemotherapy |
Trial Details
|
| Gynecologic |
Ovarian, Primary Peritoneal, Fallopian Tube |
ET743-OVC-3006: A Randomized, Open-Label Study Comparing the Combination of YONDELIS® and
DOXIL®/CAELYX® with DOXIL®/CAELYX® Monotherapy for the Treatment of Advanced-Relapsed Epithelial
Ovarian, Primary Peritoneal, or Fallopian Tube Cancer. (Phase III) R279741 (trabectedin). |
Trial Details
|
| Gynecologic |
Ovarian, Primary Peritoneal, Fallopian Tube |
GOG 0225: Can Diet and Exercise Modulate Ovarian, Fallopian Tube and Primary Peritoneal Cancer
Progression-Free Survival?
|
Trial Details
|
| Gynecologic |
Ovarian, Primary Peritoneal, Fallopian Tube |
NRG GY004: A Phase III Study Comparing Single-Agent Olaparib or the Combination of Cediranib and
Olaparib to Standard Platinum-Based Chemotherapy in Women With Recurrent Platinum-Sensitive Ovarian,
Fallopian Tube, or Primary Peritoneal Cancer
|
Trial Details
|
| Gynecologic |
Ovarian, Primary Peritoneal, Fallopian Tube |
NRG-GY005: A Randomized Phase II/III Study of the Combination of Cediranib and Olaparib Compared
to Cediranib or Olaparib Alone, or Standard of Care Chemotherapy in Women With Recurrent
Platinum-Resistant or -Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (COCOS) |
Trial Details
|
| Gynecologic |
Uterine |
NRG-GY006: A Randomized Phase II Trial of Radiation Therapy and Cisplatin Alone or in
Combination With Intravenous Triapine in Women With Newly Diagnosed Bulky Stage IB2, Stage II, IIIB,
or IVA Cancer of the Uterine Cervix or Stage II-IVA Vaginal Cancer
|
Trial Details
|
| Head and Neck |
Squamous Cell |
RTOG 0920: A Phase III Study of Postoperative Radiation Therapy (IMRT) +/- Cetuximab for
Locally-Advanced Resected Head and Neck Cancer. |
Trial Details
|
| Head and Neck (Treatment) |
n/a |
NRG-HN001: Randomized Phase II and Phase III Studies of Individualized Treatment for
Nasopharyngeal Carcinoma Based on Biomarker Epstein Barr Virus (EBV) Deoxyribonucleic Acid (DNA)
|
Trial Details
|
| Lung |
n/a |
Alliance A151216: Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial
(ALCHEMIST) |
Trial Details
|
| Lung |
n/a |
EA5142: Adjuvant Nivolumab in Resected Lung Cancers (ANVIL)-A Randomized Phase III Study of
Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-small Cell Lung Cancers
|
Trial Details
|
| Lung |
Small Cell |
Alliance A081105: Randomized Double Blind Placebo Controlled Study of Erlotinib or Placebo in
Patients With Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung
Cancer (NSCLC)
|
Trial Details
|
| Lung |
Small Cell |
STABLEMATES: STU 022015-069: JoLT-Ca A Randomized Phase III Study of Sublobar Resection (SR)
Versus Stereotactic Ablative Radiotherapy (SABR) in High Risk Patients With Stage I Non-Small Cell
Lung Cancer (NSCLC), The STABLE-MATES Trial
|
Trial Details
|
| Lung (Treatment) |
n/a |
SWOG S1400: A Biomarker-Driven Master Protocol for Previously Treated Squamous Cell Lung Cancer
(Lung-MAP) |
Trial Details
|
| Lung (Treatment) |
n/a |
SWOG S1403: A Randomized Phase II/III Trial of Afatinib Plus Cetuximab Versus Afatinib Alone in
Treatment-Naive Patients With Advanced, EGFR Mutation Positive Non-small Cell Lung Cancer (NSCLC)
|
Trial Details
|
| Lymphoma |
n/a |
EAY131: Molecular Analysis for Therapy Choice (MATCH)
|
Trial Details
|
| Melanoma (Treatment) |
n/a |
E3612: A Randomized Phase II Trial of Ipilimumab With or Without Bevacizumab in Patients With
Unresectable Stage III or Stage IV Melanoma |
Trial Details
|
| Melanoma (Treatment) |
n/a |
SWOG S1320: A Randomized Phase II Trial of Intermittent Versus Continuous Dosing of Dabrafenib
(NSC-763760) and Trametinib (NSC-763093) in BRAF V600E/K Mutant Melanoma
|
Trial Details
|
| Melanoma (Treatment) |
n/a |
SWOG S1404: A Phase III Randomized Trial Comparing Physician/Patient Choice of Either High Dose
Interferon or Ipilimumab to MK-3475 (Pembrolizumab) in Patients With High Risk Resected Melanoma
|
Trial Details
|
| Multiple Myeloma (Treatment) |
n/a |
A061202: A Phase I/II Study of Pomalidomide, Dexamethasone and Ixazomib vs. Pomalidomide and
Dexamethasone for Patients With Multiple Myeloma Refractory to Lenalidomide and Proteasome
Inhibitor-Based Therapy |
Trial Details
|
| Sarcoma |
n/a |
ARST1321: Pazopanib Neoadjuvant Trial in Non-rhabdomyosarcoma Soft Tissue Sarcomas (PAZNTIS): A
Phase II/III Randomized Trial of Preoperative Chemoradiation or Preoperative Radiation Plus or Minus
Pazopanib (NSC# 737754)
|
Trial Details
|
| Thoracic |
Small Cell/Limited |
CALGB 30610: Phase III Comparison of Thoracic Radiotherapy Regimens in Patients with Limited
Small Cell Lung Cancer Also Receiving Cisplatin and Etoposide.
|
Trial Details
|
| UGI |
Pancreas |
RTOG 0848: A Phase III Trial Evaluating Both Erlotinib and Chemoradiation as Adjuvant Treatment
for Patients with Resected Head of Pancreas Adenocarcinoma. |
Trial Details
|